全文获取类型
收费全文 | 562篇 |
免费 | 28篇 |
国内免费 | 14篇 |
出版年
2024年 | 1篇 |
2023年 | 8篇 |
2022年 | 7篇 |
2021年 | 23篇 |
2020年 | 12篇 |
2019年 | 26篇 |
2018年 | 20篇 |
2017年 | 15篇 |
2016年 | 12篇 |
2015年 | 18篇 |
2014年 | 23篇 |
2013年 | 21篇 |
2012年 | 34篇 |
2011年 | 33篇 |
2010年 | 22篇 |
2009年 | 14篇 |
2008年 | 34篇 |
2007年 | 25篇 |
2006年 | 22篇 |
2005年 | 29篇 |
2004年 | 17篇 |
2003年 | 29篇 |
2002年 | 18篇 |
2001年 | 17篇 |
2000年 | 13篇 |
1999年 | 11篇 |
1998年 | 10篇 |
1997年 | 7篇 |
1996年 | 13篇 |
1995年 | 5篇 |
1994年 | 11篇 |
1993年 | 7篇 |
1992年 | 5篇 |
1991年 | 6篇 |
1990年 | 4篇 |
1989年 | 2篇 |
1988年 | 2篇 |
1987年 | 4篇 |
1985年 | 2篇 |
1984年 | 2篇 |
1982年 | 3篇 |
1981年 | 6篇 |
1980年 | 3篇 |
1979年 | 2篇 |
1977年 | 1篇 |
1975年 | 1篇 |
1973年 | 3篇 |
1972年 | 1篇 |
排序方式: 共有604条查询结果,搜索用时 421 毫秒
1.
2.
Although many studies examine the form of sexual selection in males, studies characterizing this selection in females remain sparse. Sexual selection on females is predicted for sex‐role‐reversed Mormon crickets, Anabrus simplex, where males are choosy of mates and nutrient‐deprived females compete for matings and nutritious nuptial gifts. We used selection analyses to describe the strength and form of sexual selection on female morphology. There was no positive linear sexual selection on the female body size traits predicted to be associated with male preferences and female competition. Instead, we detected selection for decreasing head width and mandible length, with stabilizing selection as the dominant form of nonlinear selection. Additionally, we tested the validity of a commonly used instantaneous measure of mating success by comparing selection results with those determined using cumulative mating rate. The two fitness measures yielded similar patterns of selection, supporting the common sampling method comparing mated and unmated fractions. 相似文献
3.
MUNENORI NOGUCHI HIROSHI INOUE TOSHIHIRO ATAGO SHOGO NAKAMURA 《The Journal of eukaryotic microbiology》1997,44(2):127-133
ABSTRACT. The effects of organic solvents on the ATPase activity and the sliding disintegration of axonemes from Chlamydomonas were investigated. The axonemal ATPase was markedly activated by methanol accompanying with marked inhibition of the sliding disintegration of axonemes. On the contrary, glycerol inhibited the ATPase activity without serious inhibition of the sliding disintegration. As far as the axonemes are not irreversibly denatured by extremely high concentration of solvents, the effects of solvents both on the ATPase and the ability of sliding are reversible. Therefore, the inhibition of sliding accompanied by the activation of ATPase is probably due to an inability to couple the hydrolysis of ATP to sliding between dynein and microtubule in the presence of methanol. The axonemal ATPase was less sensitive to vanadate inhibition after exposure to methanol. This indicates that methanol makes the dyneinADP.Pi complex unstable and increases product release. On the other hand, glycerol and ethylene glycol seem to stabilize the force generation responsible for the sliding through stabilizing the dynein.ADP.Pi complex. 相似文献
4.
Presence of primary and secondary males in a population of the protogynous Synbranchus marmoratus 总被引:1,自引:0,他引:1
Synbranchus marmoratus , the 'swamp eel', is a protogynous diandric fish. The primary and secondary males can be distinguished from each other easily by differences in gonadal morphology. Primary males have lobular, unrestricted testes with central efferent ducts. The secondary male has a 'lamellar' testis, efferent ducts are present in the ventral region (new formation), lateral supports and it is covered by the former ovarian capsule. The length of primary male varies from 13 to 88 cm while secondary males range from 56 to 91 cm. Transitional individuals vary between 45 and 60 cm in length. The swamp eel population studied is composed of 80% primary males and 20% secondary males. Although gonadosomatic indices are always higher in primary males, they increase in secondary ones as the newly acquired stage progresses. The lamellar organization of the gonad of secondary males, the absence of this kind of testis in individuals smaller than 56 cm, and the presence of hermaphroditic fish, is evidence for protogyny in this species. 相似文献
5.
Functional Expression of P-Glycoprotein in an Immortalised Cell Line of Rat Brain Endothelial Cells, RBE4 总被引:5,自引:3,他引:2
David J. Begley Delphine Lechardeur Zheng-Duan Chen Christopher Rollinson †Michèle Bardoul †Françoise Roux Daniel Scherman N. Joan Abbott 《Journal of neurochemistry》1996,67(3):988-995
Abstract: The presence of P-glycoprotein in the cell plasma membrane limits the penetration of many cytotoxic substances into cells that express the gene product. There is considerable evidence also to indicate that P-glycoprotein is expressed as part of the normal blood-brain barrier in the luminal membranes of the cerebral capillary endothelial cells, where it presumably performs a protective function for the brain. This report describes the functional expression of P-glycoprotein in an immortalised cell line, RBE4, derived from rat cerebral capillary endothelial cells. The expression of P-glycoprotein is demonstrated by western immunoblotting and by immunogold and fluorescent staining with monoclonal antibodies. The cellular accumulation of [3 H]colchicine and [3 H]vinblastine is investigated and shown to be enhanced by the presence of azidothymidine, chlorpromazine, verapamil, cyclosporin A, and PSC 833 ([3'-keto-Bmt1 ]-[Val2 ]-cyclosporin) at 50 or 100 µ M concentration. It is concluded that the RBE4 cell line is a valuable tool for investigating the mechanisms of P-glycoprotein activity both in the blood-brain barrier and in multidrug resistance in general. 相似文献
6.
The differences in potential reproductive rate between the sexescan be used to predict the operational sex ratio and the patternsand intensity of mating competition and hence sexual selectionin a population. This article describes how one environmentalcomponent, temperature, affects potential reproductive ratesof the two sexes in the paternally brooding, sex-role reversedpipefish (Syngnathus typhle). Males brooded embryos much longer(on average 58 days) in cold water (about 10°C) than inwarmer water (35 days at about 15°C). As a consequence,the potential reproductive rate (number of eggs brooded perday) of males was significantly higher in warm water. In females,however, potential reproductive rate, i.e., number of eggs producedper day given an unlimited access to mates, was not significantlydifferent between temperatures. In both sexes, potential reproductiverate was positively related to body size. At both temperatures,females had the potential to reproduce faster than males. Asa result, the operational sex ratio will become female biasedand sex-roles reversed, as is the case in this species. Sincetemperature differently influenced the potential reproductiverates of males and females, with the sexual difference largerat lower temperatures, more intense female-female competitionis predicted at low temperatures. 相似文献
7.
Deborah A. Gust 《Primates; journal of primatology》1994,35(3):375-383
A group of 38 free ranging crested mangabeys in the Tana River Primate Reserve was studied over a 6-week period for a total
of 209.5 hr and behavioral comparisons made to a captive group of sooty mangabeys. Although quantitative comparisons between
these two mangabey species are not possible, the present data suggest that these geographically separated mangabeys share
several behavioral similarities. Copulatory behavior in both species involved a pattern of female darting and female vocalizing
following the mount by the male. Several similarities in agonistic behavior also existed: 1) The victim often returned or
stayed within 1 m of the aggressor following an agonistic episode; 2) retaliation in which the victim first fled or avoided
the aggressor, then subsequently, chased or lunged at the aggressor, typically while screaming; and 3) frequent redirection
of aggression by the victim following an agonistic episode. A dominance rank reversal occurred between the two adult male
crested mangabeys with no severe wounding. The rank reversal seemed to be related to two subsequent behaviors which included
infant carriage by the deposed alpha in the presence of the new alpha male and female demonstrations of extreme protectiveness
of their infants in the presence of the new alpha male. Both of these behaviors have been reported in the sooty mangabey group. 相似文献
8.
The operational sex ratio influences choosiness in a pipefish 总被引:3,自引:2,他引:1
If more females than males are available for mating in the breedingpopulation (i.e., the operational sex ratio, OSR, is femalebiased), males can afford to be choosy. In the pipefish (Syngnathustyphle) females compete for males, who are choosy. In natureOSRs are typically female biased, but may occasionally be malebiased. In a series of experiments, males were allowed to choosebetween a large and a small female under a perceived excessof either males or females. Under female bias, males preferredthe large female: they spent more time close to her than tothe small female; they courted the large female sooner thanthe small; and they tended to copulate sooner and more oftenwith the large female. Under male bias all these differencesvanished and males mated at random with respect to female size.Males reproduced at a faster rate under male than under femalebias because they received more eggs in their brood pouches.Thus, males switched from maximizing mate quality (i.e., beingchoosy) to minimizing the risk of not reproducing (i.e., beingquick) as the OSR became male biased. 相似文献
9.
St Lucia Lake on the north coast of Natal, South Africa, has an area of 325 km2 and is the largest estuarine complex in Africa. It consists of a 20 km tidal channel, averagingca. 400 m in width, linking the sea with the non-tidal lake which is H-shaped with a maximum length ofca. 40 km and width ofca. 20 km. Except during flood periods the depth of the lake does not exceed 2 m. The salinity gradient depends on evaporation,
the configuration of the mouth and on the input of fresh water from four rivers which discharge into the northern and western
areas of the lake. If fresh water input is high, the lake and much of the channel may be fresh. An intermediate stage features
a normal salinity gradient while a third stage shows a reversed salinity gradient with salinities in excess of 100‰ in the
upper reaches of the system. Changing salinities have marked effects on the biota. Aquatic macrophytes show cycles of appearance
and disappearance depending on salinity tolerance and the presence of dormant stages. The resident benthic faunal species
go through cycles of range expansion and contraction depending on prevailing salinities and recolonisation by dispersal phases.
To date salinities in the southern part of the lake have approached, but not exceeded, lethal levels and this has therefore
acted as a reservoir area. Catchment degradation and water abstraction are anticipated to exacerbate future salinity extremes.
This has resulted in concern for the long term viability of this Ramsar site which has major southern African populations
of hippopotamus and crocodile, provides breeding sites for South African Red Data water bird species and plays an important
nursery role for marine fish and penaeid prawns. 相似文献
10.
Summary Regeneration in hydra is considered to be morphallactic because it can occur in the absence of cell division. Whether DNA synthesis is required for regeneration or other repatterning events is not known. The question was investigated by blocking DNA synthesis with hydroxyurea and examining several developmental processes. Head regeneration, reversal of regeneration polarity and battery cell differentiation all took place in the absence of DNA synthesis. Hence, morphallactic regulation in hydra is independent of both DNA synthesis and mitosis. 相似文献